Studio clinico su ExceptionHYAL® Blossom: l'efficacia dimostrata in laboratorio

Clinical study on ExceptionHYAL® Blossom: efficacy demonstrated in the laboratory

Vulvo-vaginal atrophy is a condition that affects many women in menopause , but can also occur at a young age in the case of strong hormonal imbalances. It is a problem linked to the reduction of estrogen levels , with consequent dryness , irritation and pain during sexual intercourse . An effective solution is represented by Purofem AVV, a supplement based on ExceptionHYAL® Blossom , an advanced formulation of sodium hyaluronate .
An independent clinical study on ExceptionHYAL® Blossom confirmed its effectiveness in improving vaginal well-being and effectively soothing the symptoms of vulvovaginal atrophy.



How and why was the study conducted?

Researchers have chosen to focus on this biotechnological ingredient based on second-generation hyaluronans , characterized by a broad and specific spectrum of molecular weights , clinically tested to promote tissue rehydration and stimulate vaginal tissue regeneration . This makes it particularly effective in combating vaginal dryness and restoring the integrity of the mucous membranes.

The study involved 30 postmenopausal women (aged 45-65) suffering from vulvovaginal atrophy , divided into two groups: one group received only radiofrequency and radioporation treatment for five weeks. The other group combined these treatments with the intake of 200 mg of ExceptionHYAL® Blossom, for a period of 8 weeks. The aim of the study was to evaluate whether oral hyaluronic acid supplementation could improve the results obtained from mechanical treatments and prolong the benefits over time.


What do the results show?

The results of the study were clear and are reported in the following graph.

Women who took ExceptionHYAL® Blossom showed significant improvement compared to the group of women who did not take it. In particular, the group who took it achieved a reduction in vaginal dryness, burning and pain during sexual intercourse after just 8 weeks of treatment. At the end of the 16-week follow-up, the benefits were maintained , demonstrating the prolonged efficacy of ExceptionHYAL® Blossom even after the end of radiofrequency treatment.

ExceptionHYAL® Blossom has been shown to act not only by hydrating the tissues, but also by stimulating the endogenous production of hyaluronic acid , promoting the restoration of vaginal turgor and alleviating the symptoms of atrophy.
ExceptionHYAL® Blossom has also proven to be very useful for maintaining bone health , as it supports bone regeneration and counteracts the onset of osteoporosis, which often accompanies menopause.

Why should we trust the results?

The study was conducted by an independent company, which guarantees impartiality in the results . In addition, it was performed in accordance with international clinical guidelines , with a rigorous methodology that included randomization of participants and monitoring through standardized clinical measurement tools, such as the Vaginal Health Index (VHI) and the Visual Analogue Scale (VAS)

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